FRECUENCIA ALELICA PDF

Para poder predecir las frecuencias genotípicas, frecuencia de un gen o frecuencia fenotípica de una población se puede hacer solo si se. Frecuencia alélica del gen de la calpastatina en el ganado criollo limonero. José Atilio Aranguren1, María Gabriela Portillo2,. Carolina Flores Rondón3, Yenen. allele frequency · Frecuencia alelica (sinonimo: frecuencia genica). English to Spanish. allele-specific oligonucleotide testing · Estudios de oligonucleotidos.

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Factor V Leiden GA and prothrombin-GA alleles among patients with deep venous thrombosis and in the general population from Spain. Departament de Medicina Preventiva.

Translation glossary: Genetics glossary

Factor V leiden and the -GA variant of prothrombin gene are associated to a higher risk of deep venous thrombosis. Factor V Leiden ga and prothrombin-ga alleles were genotyped in individuals frecuebcia the Spanish general populations and in patients with DVT.

The presence of DVT was confirmed by phlebography. Allelic frequencies and the DVT risk associated with these variants were estimated.

Allelic frequencies for the factor V Leiden GA allele were 0. The frequencies for the prothrombin-GA allele were 0. After adjustment for age and gender, the odds ratio for DVT, associated with the presence of GA allele was 2.

On the contrary, the GA allele is associated by itself with a two fold increase in Alellca risk in this population although without reaching statistical significance due to its low frequency.

Frecuencias genotípicas, fenotípicas y alelicas by Mary Garcia on Prezi

Por ello, los objetivos de este estudio son: La primera muestra estaba compuesta por sujetos varones y mujeres adultos residentes en la provincia de Valencia. Las condiciones de la PCR fueron: Los resultados de cada electroforesis fueron interpretados por dos investigadores, repitiendo en caso de discrepancia si la hubiese. Se agruparon los portadores homocigotos y heterocigotos para los alelos factor V Leiden GA y protrombina-GA, se compararon sus frecuencias en ambas poblaciones mediante el test de Ji cuadrado.

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Como se aprecia en la Tabla 4, las frecuencias latinoamericanas son compatibles con los flujos migratorios procedentes de la Europa meridional que se dieron a partir de finales del s.

No obstante, otros estudios, no logran evidenciar un claro aumento de riesgo asociado a este alelo 8,9,15, A single genetic origin for a common Caucasian risk factor for venous thrombosis. Br J Haematol ; Factor V Leiden with deep venous thrombosis. Clin Lab Sci ; High risk of thrombosis in patients homozygous for factor V Leiden activated protein C resistance.

A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Prothrombin and the prothrombin G to A polymorphism: Blood Rev ; Factor V Leiden and prothrombin gene GA mutation in children with venous thromboembolism.

La mutacion H63D del gen HFE se asocia con un riesgo aumentado de carcinoma hepatocelular

Thromb Haemost ; The prothrombin A allele is the most prevalent genetic risk factor for venous thromboembolism in the Alslica population. Risk of venous thrombosis in carriers of the prothrombin GA variant and factor V Leiden and their interaction freduencia oral contraceptives. Lucotte G, Mercier G. Population genetics of factor V Leiden in Europe. Blood Cells Mol Dis ; Med Clin ; Incidence of post-thrombotic syndrome and its association with various risk factors in a cohort of Spanish patients after one year of follow-up following acute deep venous thrombosis.

Cold Spring Harbor Laboratory Press; Cardiovasc Surg ; The prothrombin A allele and the factor V Leiden are associated with venous thrombosis but not with early coronary artery disease. Blood Coagul Fibrinolysis ; Inherited thrombophilic risk factors and venous alelics Prothrombin gene G-A mutation in the Turkish alelkca.

Am J Hematol ; Prevalence of genetic mutations that predispose to thrombophilia in a Greek Cypriot population. Clin Appl Thromb Hemost ; 6: Prevalence of the prothrombin GA mutation in the Irish populations: The risk of recurrent venous thromboembolism in carriers and non-carriers of the GA allele in the coagulation factor V gene and the GA allele in the prothrombin gene.

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Frechencia V Leiden RQ and risk of venous thromboembolism: Clin Genet ; Prevalence of factor V Leiden and the GA mutation of the prothrombin gene in a random group of patients with thrombotic episodes. Large-scale screening for factor V Leiden mutation in a north-eastern German population.

Polymorphisms of fibrinogen, factor VII and factor V genes: Comparison of allele frequencies in different ethnic groups. Seligsohn U, Zivelin A.

Thrombophilia as a multigenic disorder. Phylogeography of mitochondrial DNA in western Europe.

Ann Hum Genet ; Assessment of the G to A prothrombin variant in a sample of patients from the French Basque Country with various thrombophilic conditions. Ann Hematol ; World distribution of factor V Leiden.

Lancet ; ; Thromb Frecuejcia ; Prevalence of the factor V-Leiden mutation in four distinct American ethnic populations. Am J Med Genet ; 19; Ann Intern Med ; Asymptomatic homozygous nt G to A aleloca polymorphism in two blood donors belonging to two different kindreds. Clin Appl Thromb Hemost ; 5: Khoury MJ, Yang Q. The future of genetic studies of complex human diseases: Genetic epidemiology and the future of disease prevention and public health.

Epidemiol Rev ; Relationship between medical genetics and public health: Am J Med Genet ; Prevalence of three prothrombotic polymorphisms: Thromb Res ; 1; Factor V Leiden and prothrombin GA variant are risk factors for venous thromboembolism in the Argentinean population.

Geographic distribution of the G to A prothrombin variant. Prevalence of the prothrombin gene variant ntA in venous thrombosis and frecuenccia disease.

Prevalence of factor V Leiden mutation in various populations. Genet Epidemiol ; Factor V Leiden mutation in the Argentinian population. Recibido el 25 de abril, Aceptado el 13 de julio,